My research

Here you can find out about peer-review publications in different academic journals.


Inhibitory control in neuronal networks relies on the extracellular matrix integrity (English)

Journal: Cellular and Molecular Life Sciences

Inhibitory control is essential for the regulation of neuronal network activity, where excitatory and inhibitory synapses can act synergistically, reciprocally, and antagonistically. Sustained excitation-inhibition (E-I) balance, therefore, relies on the orchestrated adjustment of excitatory and inhibitory synaptic strength. While growing evidence indicates that the brain’s extracellular matrix (ECM) is a crucial regulator of excitatory synapse plasticity, it remains unclear whether and how the ECM contributes to inhibitory control in neuronal networks. Here we studied the simultaneous changes in excitatory and inhibitory connectivity after ECM depletion. We demonstrate that the ECM supports the maintenance of E-I balance by retaining inhibitory connectivity. 


Tenascin-C preserves microglia surveillance and restricts leukocyte and, more specifically, T cell infiltration of the ischemic brain (English)

Journal: Brain, Behavior and Immunity

TnC deficiency reduced tissue surveillance by microglial cells. Concomitantly, the number of infiltrating leukocytes and, more specifically, T cells was increased in the ischemic brain parenchyma of TnC deficient compared with wild type mice. Ischemic injury and neurological deficits were not affected by TnC deficiency. We propose that the reduced microglia surveillance in TnC deficient mice might favour leukocyte accumulation in the ischemic brain.


Deactivation of ATP-Binding Cassette Transporters ABCB1 and ABCC1 Does Not Influence Post-ischemic Neurological Deficits, Secondary Neurodegeneration and Neurogenesis, but Induces Subtle Microglial Morphological Changes (English)

Journal: Frontiers in Celullar Neuroscience

By summarizing the currently available evidence obtained by in vitro research, animal experimentation and human studies, we aim to propose a new direction for the future investigation of stroke recovery.

ENCODS : A novel initiative to inspire young neuroscientists (English)

Journal: European Journal of Neuroscience

The European Neuroscience Conference by Doctoral Students (ENCODS) is a novel and unconventional scientific conference organized by and for doctoral neuroscience students from around the world. In this way, ENCODS intends to meet the interests of young researchers and promotes the exchange of personal experiences and the establishment of research networks at an early career stage. With its focus on the next generation of neuroscientists, this conference has a special emphasis on currents trends and future developments in the field.


Role of immune responses for extracellular matrix remodeling in the ischemic brain (English)

Journal: Therapeutic Advances in Neurological Disorders

In this review, we focus on the interplay between neuroinflammatory cascades and ECM in the ischemic brain. By summarizing the currently available evidence obtained by in vitro research, animal experimentation and human studies, we aim to propose a new direction for the future investigation of stroke recovery.

Topological remodeling of cortical perineuronal nets in focal cerebral ischemia and mild hypoperfusion (English)

Journal: Matrix Biology

In line with the activation of neural plasticity under mild stress stimuli, we provide evidence that topological conversion of PNNs can support post stroke neural rewiring.


Assessment transcallosal Diaschisis in a model of focal cerebral ischemia in rats (Spanish/English)

Journal: Colombia Médica

The immunoreactive changes to NeuN support the process of interhemispheric diaschisis. Changes in immunoreactivity could indicate metabolic stress secondary to the disruption in connectivity to the site of lesion.


El Problema de la Consciencia y su brecha explicativa en la Psicología (Spanish)

Journal: Diversitas: Perspectivas en Psicología

El presente artículo plantea una reflexión sobre la brecha explicativa en la dificultad de la consciencia en el marco del problema mente-cuerpo y su estudio en la psicología.